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In a randomized placebo-controlled trial that included 101 participants with fibromyalgia, those who received 3 mg or 5 mg of melatonin nightly in addition to antidepressant therapy with fluoxetine had improvement on Fibromyalgia Impact Questionnaire scores after eight weeks

Nutrient absorption can be affected by individual digestive system health Some supplements may cause gastrointestinal side effects 3

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